By Abraham Fisher, Maurizio Memo, Fabrizio Stocchi, Israel Hanin
Proceedings of the seventh overseas convention on Alzheimer’s ailment and Parkinson’s ailment (ADPD), held March 9-13, 2005 in Sorrento, Italy.
The material of the ADPD meetings is exclusive in that it bargains not just with matters similar separately to Alzheimer’s illness and Parkinson’s disorder, but additionally with the mixing of those and different comparable ailments. the main updated concepts and study findings are illustrated during this quantity, masking subject matters similar to immunology, neuroscience, pharmacology, genetics, molecular biology, biochemistry and the heritage, epidemiology, medical phenomenology, analysis, imaging, remedy ,and destiny views of Alzheimer’s and Parkinson’s Diseases.
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Extra info for Advances in Alzheimer's and Parkinson's Disease: Insights, Progress, and Perspectives (Advances in Behavioral Biology)
Acharya S, Foster PL, Brooks P, Fischel R. The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair. Mol Cell 2003;12:233–246. 3 Impaired DNA Repair Systems 21 5. Bellacosa A. Functional interactions and signaling properties of mammalian DNA mismatch repair proteins, Cell Death Differ 2001;8:1076–1092. 6. Rolig RL, McKinnon PJ. Linking DNA damage and neurodegeneration. Trends Neurosci 2000;23:417–424. 7. Brooks PJ. DNA repair in neural cells: basic science and clinical implications.
39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. Chapter 3 Impaired DNA Repair Systems: Generation of Mitochondrial Dysfunction and Increased Sensitivity to Excitotoxicity Simona Francisconi, Mara Codenotti, Erminia Poli, Daniela Uberti, Giulia Ferrari-Toninelli, and Maurizio Memo Introduction Preservation of genomic stability is an essential biological function, and cells engage efficient mechanisms to maintain DNA stability over time and prevent the generation and the persistence of impaired cells that may be detrimental to the organism.
Role of cholinesterase inhibitors in Parkinson’s disease and dementia with Lewy bodies. J Geriatr Psychiatry Neurol 2004;17:164–171 22. Emre M, Aarsland D, Albanese A, et al. Rivastigmine for dementia associated with Parkinson’s disease. N Engl J Med 2004;351:2509–2518. Chapter 2 Neurogenetics in Parkinson’s Disease Yoshikuni Mizuno and Nobutaka Hattori Introduction To date, 11 forms of familial Parkinson’s disease (PD) have been mapped to different loci on chromosomes. As a result, six causative genes have been identified: alpha-synuclein , parkin , UCH-L1 , PINK1 , DJ-1 , and LRRK2 [6,7].
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