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By James T Irving; Felix Bronner; Gideon A Rodan

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1936). Shohl et al. (1933) found in much the same way that the phosphorus intake was a limiting factor in the control of the calcium content of the body in the rat. 50% calcium. Although all the animals grew at the same rate and looked equally healthy, those on the higher calcium intake contained more calcium during the growth period, the difference gradually disappearing as the rats became middle-aged. 35% calcium till 50 days later. Fairbanks and Mitchell (1936) also found that the carcass calcium increased with high calcium contents of the diet.

Since then many more analyses have been made and more recent figures have been reported by Coons (1935), lob and Swanson (1934), and Givens and Macy (1933). The latter authors found the calcium content to rise in an apparently exponential way, when plotted against age, to a final calcium content of 21 g at term, the greatest calcium demand coming in the last 3 months of gestation. 4 kg. 4 kg. 0% on a fat-free body basis. IN GROWING CHILDREN Knowledge of the calcium content of the body of the child during growth is of importance in assessing the dietary calcium requirements of children, but little direct information exists on this subject.

This seems to be the case for the rat and rhesus, but does not apply to the guinea pig. The pig placenta is of the epitheliochorial type, with six tissue layers separating the maternal and fetal blood, and is the most primitive of placentas. In spite of this apparent structural barrier, calcium and phosphorus appear to traverse it easily. Kronfeld et al. (1971) have carried out kinetic analyses of placental calcium transfer in monkeys and sheep, and have calculated the rate of active transport in the two species.

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